Sex specific differences in 24 hours urinary excretion of steroid hormone metabolites. Studer, Hubert; Ackermann, Günter, 2009. quint-essenz : Potenziale in Projekten erkennen und nutzen. (DOC), Comparison of baseline characteristics. focus - das Magazin von Gesundheitsförderung Schweiz. Moreover, AVP stimulates the expression of 11β-hydroxysteroid-dehydrogenase-type 2 (11β-HSD2) in mineralocorticosteroid cells. Court decisions create posi-tive externalities for future litigants which will not occur if a dispute is settled out of court. Switzerland : Stamps [Year: 2017] [3/6]. Vol. We are one of the leading Swiss competence centres in the fields of nutrition, health, society and the environment. Proteolytic cleavage sheds the ectodomain of α-klotho (soluble α-klotho) as an endocrine substance into blood, urine and cerebrospinal fluid. D... Urinary creatinine excretion is used as a marker of completeness of timed urine collections, which are a keystone of several metabolic evaluations in clinical investigations and epidemiological surveys. We assessed if sodium and potassium consumption present a seasonal pattern. 44 / 147. info@zhaw.ch. Thus, in addition to its role in bile acid synthesis, where it converts cholesterol to 27-hydroxycholesterol (27-OHC), CYP27A1 may also be atheroprotective. Luzern: Interact. Wirkungsorientierte Gesundheitsförderung in der Schule. RRI correlates positively with arteriolosclerosis in damaged kidneys and predicts progressive renal dysfunction. Amélioration de la qualité. Suchtmagazin 41(3), S. 23-26. The central issue in organ transplantation remains suppression of allograft rejection. We conducted a meta-analysis of genome-wide association studies for estimated glomerular filtration rate (eGFR), combining data across 133,413 individuals with replication in up to 42,166 individuals. Quantitative urinary steroid excretion values measured by GC-MS and published since 1986 in adults are shown. The number of participants is indicated for each characteristic and sex group. February 19, 2020 ... Bella is seen in an oversized grey suit outside of the Haider Ackermann show in Paris. However, population-based reference intervals for adults do not exist. 27(3), S. 67-72. Ungefähr 10% der Sarkoidosepatienten haben im beobachteten Zeitraum eine Hyperkalzämie. We guarantee excellent degree and continuing education programmes in engineering disciplines. However, reference values in the general population and information on familial aggregation are largely lacking. Fur... 11β-Hydroxsteroid dehydrogenase 2 (11β-OHSD2) protects the nonselective renal mineralocorticoid receptor from the endogenous glucocorticoid cortisol. Office and 24-hour ambulatory blood pressure were measured using validated devices. Essential hypertension is a complex trait, involving multiple genes and environmental factors. max; Individual level ... Kathrin Ackermann is a PhD candidate and research assistant at the Institute of Political Science, University of Bern (Switzerland). Gesundheit und Lebensqualität im Alter. Stuttgart: Thieme. Categorical variables are described by % and continuous variables by their mean±standard deviation or by their median;25th-75th percentiles. Since inflammation is characteristic of CKD and associates with increased plasma FGF23 we examined whether inflammation directly stimulates FGF23. As diuretics influence the renal handling of potassium, we analyzed the impact of 13 commonly used diuretics on 11β-OHSD2. If you use Google Maps, Google will register it. A potential intermediate mechanism could be hormone-related by disturbing steroidogenesis in gonads and adrenal glands. Boston Veterans Affairs Healthcare, Boston, United States, University Medicine and Ernst Moritz Arndt University Greifswald, Cardiovascular End Points and Mortality Are Not Closer Associated With Central Than Peripheral Pulsatile Blood Pressure Components, Ambulatory Blood Pressure in Relation to Plasma and Urinary Manganese, Parathyroid Hormone and Plasma Phosphate Are Predictors of Soluble α-Klotho Levels in Adults of European Descent, Renal Resistive Index Is Associated With Inactive Matrix Gla (c-Carboxyglutamate) Protein in an Adult Population-Based Study, Use of day and night urinary iodine excretion to estimate the prevalence of inadequate iodine intakes via the estimated average requirement cut-point method, Associations of ‘Relative corticosterone deficiency’ with genetic variation in CYP17A1 and metabolic syndrome features, Mineralocorticoid receptor and diabetes: in favour of other corticosteroids than aldosterone, Tumor necrosis factor stimulates fibroblast growth factor 23 levels in chronic kidney disease and non-renal inflammation, Reference intervals for the urinary steroid metabolome: The impact of sex, age, day and night time on human adult steroidogenesis, Urinary Sex Steroid and Glucocorticoid Hormones Are Associated With Muscle Mass and Strength in Healthy Adults, Urinary steroid profiling in women hints at a diagnostic signature of the polycystic ovary syndrome: A pilot study considering neglected steroid metabolites, Five‐year outcomes in kidney transplant patients randomized to everolimus with cyclosporine withdrawal or low‐exposure cyclosporine versus standard therapy, FO044UROMODULIN REFLECTS NEPHRON MASS IN THE GENERAL POPULATION AND KIDNEY DONORS, Associations of Urinary Caffeine and Caffeine Metabolites With Arterial Stiffness in a Large Population-Based Study, Association of 24-Hour Blood Pressure With Urinary Sodium Excretion In Healthy Adults, Copeptin and insulin resistance: effect modification by age and 11 β-HSD2 activity in a population-based study, Genome-Wide Meta-Analysis Unravels Interactions between Magnesium Homeostasis and Metabolic Phenotypes, Urinary Cadmium Excretion Is Associated With Increased Synthesis of Cortico- and Sex Steroids in a Population Study, A population-based approach to assess the heritability and distribution of renal handling of electrolytes, Seasonality of sodium and potassium consumption in Switzerland. 1 INTRODUCTION. However, the heritability of these processes, the first step in gene discovery, is poorly known. 4 The Department for BioMedical Research (DBMR) is a Research Department of the Faculty of Medicine at the University of Bern. Within-sex differences were determined by Wilcoxon signed-rank test... Reference curves of steroid compounds. The handling of electrolytes by the kidney is essential for homeostasis. Gesundheitsförderung Schweiz. or measures is clinically relevant. Crosses indicate data points, the solid line represents the linear regression curve and the dotted lines the 95% confidence interval. To study the r... Background Increased renal resistive index (RRI) has been associated with target organ damage as well as renal and cardiovascular outcomes. Rho values were ra... Statistical methods. Traffic Rank: Daily Visitors: Daily Page Views: Daily Ads Revenue: Net Worth: 296731 : 753 Min: 452 Max: 1,130 Zeitschrift für Gesundheitsförderung. α-klotho is an integral membrane protein, that serves as a co-receptor for fibroblast growth factor 23 (FGF23) in conjunction with cognate fibroblast growth factor receptors. Calibration curves are shown for all analytes injected on column in the range from 39 to 20000 fmol. Qualität braucht Kriterien. Ackermann, Günter, 2014. (DOC), Association between PCOS, age and body mass index (BMI) with four classifiers derived from the urine steroid hormone metabolome to predict PCOS. Objective Sound Design: Sebastian Bark, Jeff McGrory (Torsten Schwarzbach) Video Design: Miles Chalcraft (Noam Gorbat) Costume Design: Ingken Benesch. Thus, drugs inhibiting 11beta-OHSD2 might enhance urinary loss of potassium. Focus 24, S. 14–17. Max HALDIMANN of Bundesamt für Gesundheit, Schweiz, Bern (BAG) | Read 54 publications | Contact Max HALDIMANN Studer, Hubert. 51 (1). Daniel ACKERMANN of Inselspital, Universitätsspital Bern, Bern | Read 95 publications | Contact Daniel ACKERMANN. Weber, Dominik; Abel, Bettina; Ackermann, Günter; Biedermann, Andy; Bürgi, Flavia; Kessler, Claudia; Schneider, Jvo; Steinmann, Ralph; Widmer Howald, Franziska, 2016. : Un outil pour la catégorisation des résultats de projets de promotion de la santé. Die Hyperkalzämie ist eine häufige Komplikation der Sarkoidose. Born in 1963 in Germany, Franz Ackermann lives and works between Berlin and Miami. We are the largest training and research centre in Switzerland for occupational therapy, midwifery, nursing and physiotherapy, as well as for research and development in these fields. Urinary cadmium (Cd) excretion is associated with cancer and cardiovascular morbidity. The second story is about a reporter and … Descriptive analyses of steroid compounds. (previous page) () Urinary steroid metabolomics by GC-MS is an established method in both clinical and research settings to describe steroidogenic disorders. The Soviet Union is sending its prisoners of war home. Summer, 1954. Furosemide Inhibits 11 -Hydroxysteroid Dehydrogenase Type 2, Furosemide Inhibits 11β-Hydroxysteroid Dehydrogenase Type 2 1, Department of Nephrology, Hypertension and Clinical Pharmacology, Department of Life and Reproduction Sciences, Service de néphrologie et consultation d'hypertension, University Clinic for Nephrology, Hypertension and Clinical Pharmacology, Institut universitaire de médecine sociale et préventive. Data from three cross-sectional, population-based studies, Reference values for the urinary steroid metabolome: the impact of sex and age on human adult steroidogenesis, Urinary cadmium excretion is associated with increased synthesis of cortico- and sex steroids in a family-based Swiss population study, MP108UROMODULIN MODULATES THE EFFECT OF SODIUM ON BLOOD PRESSURE IN THE GENERAL POPULATION, Genome-wide association study of caffeine metabolites provides new insights to caffeine metabolism and dietary caffeine-consumption behavior, Relation of 24-hour urinary caffeine and caffeine metabolite excretions with self-reported consumption of coffee and other caffeinated beverages in the general population, OP.2A.02] UROMODULIN MODULATES THE EFFECT OF SALT ON BLOOD PRESSURE IN THE GENERAL POPULATION, Fibroblast growth factor 23 and markers of mineral metabolism in individuals with preserved renal function, Sociodemographic, behavioral and genetic determinants of allostatic load in a Swiss population-based study, MP359FGF23 AND MARKERS OF MINERAL METABOLISM IN SUBJECTS WITH PRESERVED RENAL FUNCTION, Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes, Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function, Associations of Urinary Uromodulin with Clinical Characteristics and Markers of Tubular Function in the General Population, New anthropometry-based age- and sex-specific reference values for urinary 24-hour creatinine excretion based on the adult Swiss population, CYP17A1 Enzyme Activity Is Linked to Ambulatory Blood Pressure in a Family-Based Population Study, Heritability of ambulatory and office blood pressure in the Swiss population, 4B.05: PLASMA COPEPTIN IS ASSOCIATED WITH INSULIN RESISTANCE IN A SWISS POPULATION-BASED STUDY, 5C.09: HERITABILITY OF RENAL FUNCTION PARAMETERS AND ELECTROLYTE LEVELS IN THE SWISS POPULATION, Inactive Matrix Gla-Protein Is Associated With Arterial Stiffness in an Adult Population-Based Study, IgA nephropathy and purpura Schönlein-Henoch - A broad spectrum, Associations of Ambulatory Blood Pressure With Urinary Caffeine and Caffeine Metabolite Excretions, Copeptin Is Associated with Kidney Length, Renal Function, and Prevalence of Simple Cysts in a Population-Based Study, COPEPTIN LEVELS ARE ASSOCIATED WITH RENAL FUNCTION, RENAL LENGTH AND SIMPLE CYSTS, Epidemiology of Masked and White-Coat Hypertension: The Family-Based SKIPOGH Study, Effect of Cyp27A1 gene dosage on atherosclerosis development in ApoE-knockout mice, Reference Values and Factors Associated With Renal Resistive Index in a Family-Based Population Study, Sodium/hydrogen exchanger NHA2 is critical for insulin secretion in -cells, Heritability, determinants and reference values of renal length: A family-based population study, The sodium-dependent ascorbic acid transporter family SLC23, Échographie rénale dans la population générale suisse : premiers résultats d’une étude multicentrique, Uninephrectomy reduces 11 -hydroxysteroid dehydrogenase type 1 and type 2 concomitantly with an increase in blood pressure in rats. Here we show that NHA2 is present in rodent and human β-cells, as well as β-cell lines. In childhood, it most frequ... Intake of caffeinated beverages might be associated with reduced cardiovascular mortality possibly via the lowering of blood pressure. We measured daytime and night time urinary excretion of 40 steroid metabolites by GC-MS in 1128 adult participants of Eur... Calibration curves. Ackermann, Günter, 2018. The aim of the study was to analyze... We investigated factors associated with masked and white-coat hypertension in a Swiss population-based sample. The factors associated with uromodulin excretion in the normal population remain largely unknown, and were therefore explored in this study. Gesundheitsförderung Schweiz, Hrsg., Bern und Lausanne. (PDF). 1, 2 The risk of thrombotic complications is particularly high in patients admitted to the intensive care unit (ICU). We use scientific methods to clarify psychological problems in the field of applied psychology. Circulating FGF23 is elevated in chronic kidney disease (CKD) and independently associated with poor renal and cardiovascular outcomes and mortality. The available number of participants is indicated for each metabolite stratified for sex. In: Kirch W, Middeke M, Rychlik R (Hrsg): Aspekte der Prävention. Erhard Göpel and Barbara Göpel, ed. In this population-based study, reference values were generated for renal length, and the heritability and factors associated with kidney length were assessed. Published urinary steroid excretion reference values. A digital ... Max und Elsa Beer-Brawand Fonds & die Mittelbauvereinigung Uni Bern Evaluation des Nationalen Rauchstopp-Programms über den Zeitraum von Juli 2014 – Dezember 2017 : Synthese von Projektstatistiken, Evaluationsergebnissen, wissenschaftlichen Studien, internationalen Leitlinien und Expertenmeinungen im Rahmen einer Kontributionsanalyse (DOC), Comparison of steroid hormone metabolite ratios to assess steroid enzyme activities. Katharina-Sulzer-Platz 9 Ein Modell zur systematischen Kategorisierung der Ergebnisse von Gesundheitsförderungsprojekten. S. 183-194 S. 63. Qualität in der Gesundheitsförderung. Travel as an experience, displacement and observation are the notions at the heart of his paintings and installations. We therefore hypothesize that 11beta-hydroxysteroid dehydrogenase 2 (11beta-HSD2), which protects mineralocorticoid receptors (MR) from glucocorticoster... 11Beta-hydroxsteroid dehydrogenase 2 (11beta-OHSD2) protects the nonselective renal mineralocorticoid receptor from the endogenous glucocorticoid cortisol. 277-290 Whether AVP also affects kidney structure in the general population is unknown. Bern und Lausanne. Hyponatre... Unlabelled: Common genetic variants in CYP17A1 associate with higher blood pressure, putatively from impaired 17 alpha-hydroxylase activity and mineralocorticoid excess.

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